BEGIN:VCALENDAR VERSION:2.0 PRODID:-//KnowAFest//Campus Events//EN BEGIN:VEVENT UID:eventsphere-49943@www.knowafest.com DTSTAMP:20261008T224714Z DTSTART:20171109T183000Z DTEND:20171110T182959Z SUMMARY:National Seminar on Cancer Biology: A Mathematical Approach LOCATION:Kongu Engineering College\, Erode DESCRIPTION:

ABOUT THE SEMINAR
\nCancer is an abnormal growth of cel ls caused by multiple changes in gene expression leading to dysregulated b alance of cell proliferation and cell death and ultimately evolving into a population of cells that can invade tissues and metastasize to distant si tes\, causing significant morbidity and\, if untreated\, death of the host . Cancer is caused when cells within the body accumulate genetic mutations and start to grow in an uncontrolled manner. Understanding how cancer dev elops and progresses\, including how gene mutations drive the growth and s pread of cancer cells\, and how tumours interact with their surrounding en vironment\, is vital for the discovery of new targeted cancer treatments.< br />\nOver the past 15 years\, drugs have emerged that target cancer meta bolism\, either directly through enzymes that facilitate metabolic reactio ns or indirectly through signaling pathways. Targeted therapy is typically less damaging to normal cells than chemotherapy. However\, cancer cells a re extremely robust for survival and often completely insensitive to pertu rbations or develop resistance over time. Assessing and improving the util ity of mathematical models in the context of systems biology will continue to be an active area of research.
\nMathematical and statistical mod els are capable of integrating biological knowledge that is outside of the observational data. Cancer is a complex process that changes in space and in time. Even the same cancer can be different between two patients. Math ematics\, as the language of the physical universe\, is very good at descr ibing and predicting phenomena that change over time. A major challenge in cancer research is that our data is a static snapshot of a dynamic proces s. Mathematics is used to understand the dynamics.
\nAim of the semin ar is to apply mathematical methods and theories to the study of cancer an d describe recent developments in mathematical modeling and mathematical a nalysis of certain problems arising from cell biology. This seminar acts a s a forum for the intersection of mathematics and biology\, and increasing ly in the research setting\, the push to have engineers and mathematicians talking to biologists\, thus improving communication among the discipline s. While interdisciplinary training has generally been frowned upon\, this broadening of awareness\, can produce a deeper understanding of how the p hysical\, mathematical\, clinical and biological sciences are linked.
\nCOURSE TOPICS
\n Molecular Basis to Cancer
\n Modelling the Interaction of Dietary Fibres and Carcinogens Causing Colorectal Canc er
\n Recent Advances and Research Issues in Cancer Biology

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